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Physical exercise has numerous effects on the human body, including the immune system. Which was quoted by Mathew et. Al in the study they did to check the effects of exercise on immunity. It is well known that mild to moderate exercise helps to boost the overall immune system and activity of key white blood cells.
Although exercise immunology is considered a relatively new area of scientific discovery with 90% of papers published after 1990, some of the earliest studies were published well over a century ago. For example, in 1902, Larra bee provided evidence that changes in white blood cell differential counts in Boston marathon runners paralleled those seen in certain diseased conditions. He also observed that “the exertion had gone far beyond physiological limits and our results certainly show that where this is the case, we may get a considerable leukocytosis of the inflammatory type.”
Which basically meant that prolonged strenuous running in marathon runners lead to a decreased function of white blood cells.
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